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Asentra contains the active substance sertraline. Sertraline belongs to a group of selective serotonin reuptake inhibitors (SSRIs), these drugs are used to treat depression and anxiety disorders. Asentra is used to treat: Depression and prevent recurrence of depression (in adults). Social anxiety disorder (in adults). Post traumatic stress disorder (PTSD) (in adults). Panic disorder (in adults). Obsessive compulsive disorder (OCD) (in adults and adolescents aged 6 to 17 years).

Do not use Asentra •If you are allergic (hypersensitive) to sertraline or any of the other components of Asentra. •If you are taking or have been treated with drugs called monoamine oxidase (MAO) inhibitors (such as selegiline, moclobemide) or with drugs like MAOIs (such as linezolid). If you stop taking sertraline, you must wait at least one week before starting treatment with MAOIs. After stopping treatment with MAOIs, you should wait at least 2 weeks before you start treatment with sertraline. •If you are taking another medicine containing pimozide (an antipsychotic medication). Take special care with Asentra Not every product is suitable for everyone. Please tell your doctor before using Asentra, if you have or have recently undergone one of the following states: •Serotonin syndrome. In rare cases, this syndrome can occur when using some drugs the same with sertraline. (For symptoms, see section 4. Possible side effects). Inform your doctor if you have this syndrome in the past. •Low sodium in the blood, because this can occur as a result of treatment with Asentra. Also, you should tell your doctor if you use certain drugs for high blood pressure, since these drugs can alter the concentration of sodium in the blood. •Be careful if you are elderly, because you can present a higher risk of having low blood sodium (see above). •Liver disease, your doctor can decide if the Asentra dose reduction. •Diabetes blood sugar levels can be modified by Asentra and diabetes medication will be adjusted. •Epilepsy or epileptic seizures. If you have a fit (seizure), contact your doctor immediately. •If you have suffered from manic-depressive illness (bipolar disorder) or schizophrenia. If you have a manic episode, contact your doctor immediately. •If you have or previously had suicidal thoughts (see below – thoughts of suicide and worsening of your depression or anxiety). •If you have bleeding disorders or if taking medicines such as aspirin or warfarin •If you are a child or adolescent under 18 years. Asentra should only be used to treat children and adolescents aged 6 to 17 years, suffering from obsessive compulsive disorder. If you are treated for this condition, your doctor will want to monitor you closely (see below Use in children and adolescents) •If you are receiving electroconvulsive therapy (ECT)

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without prescription. Some medicines may affect Asentra action; can reduce the effectiveness of other drugs used at the same time. Medicines called monoamine oxidase (MAO) inhibitors such as moclobemide (for depression) and selegiline (for Parkinson’s disease) and the antibiotic linezolid. Do not use Asentra with MAOIs. Medications used to treat mental disorders (pimozide). Do not use Asentra with pimozide. Tell your doctor if you use the following drugs: •Herbal medicines containing St John’s wort (Hypericum perforatum). Effect of St. John’s wort may take up to 1-2 weeks. Tell your doctor. •Products containing the amino acid tryptophan. •Medicines to treat severe pain (eg tramadol). •Medicines to treat migraines (eg sumatriptan) •Drugs that prevent normal blood clotting (warfarin). •Medicines to treat pain / arthritis (inflammatory drugs (NSAIDs) such as ibuprofen, aspirin). •Sedatives (diazepam). •Diuretics. •Medicines for epilepsy (phenytoin). •Medications to treat diabetes (tolbutamide). •Medicines to treat ulcers and reduce excessive stomach acid (cimetidine) •Medicines to treat mania and depression (lithium). •Other drugs to treat depression (such as amitriptyline, nortriptyline). •Medicines to treat schizophrenia and other mental disorders (such as perphenazine, levomepromazine and olanzapine).

Asentra use with food and drink
Asentra tablets can be taken with or without food. You should not drink alcohol while taking Asentra.


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